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Do adipokines contribute to cardiovascular disease in psoriasis patients?

Posted on : 26-06-2011 | By : Fabio Sanchez | In : Research

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Cytokines are hormones that can modify cell behavior. Adipokines are cytokines produced by fat tissue that also function as hormones regulating many metabolic functions. Gerdes S, Rostami-Yazdi M and Mrowietz U. wrote a review article in Experimental Dermatology that discuses the possibility that adipokines contribute to the metabolic imbalances that make psoriasis patients more susceptible to cardiovascular disease. Read the summary to the paper at: Exp Dermatol. 2011 Feb;20(2):81-7. Adipokines and psoriasis.

Inflammatory epilepsy?

Posted on : 20-06-2011 | By : Fabio Sanchez | In : Research

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Could inflammation cause epilepsy? Many researches think that is the case. This is a new and exciting field of research that might bring about new ways to manage this terrible disease.

Here is one paper that suggests TNF alpha, an immune molecule with proinflammatory properties, can affect the way nerve cells respond to their environments.
 
Kiarash Riazi, Michael A. Galic, J. Brent Kuzmiski, Winnie Ho, Keith A. Sharkey, and Quentin J. Pittman
Proc Natl Acad Sci U S A. 2008 November 4; 105(44): 17151–17156. PMC:2579393

Inflammasomes on the spotlight!

Posted on : 11-06-2011 | By : Fabio Sanchez | In : Research

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The reputed scientific journal Nature Review of Immunology has published the paper "Emerging inflammasome effector mechanisms." by M. Lamkanfi (Nat Rev Immunol. 2011 Mar;11(3):213-20.). The paper aims at describing how inflammasomes might be operating in order to regulate the natural desfenses in the organism, which, we call innate immunity. It also discusses the role of inflammasomes in tissue repair.
Fabio Sánchez

Research about inflammation

Posted on : 11-06-2011 | By : Fabio Sanchez | In : Research

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This section of the www.inflammes.com website will bring you descriptions of recent advances in the research of inflammation related topics. I will add a comment of my own to simplify some of the concepts described in the original papers. This selection reflects my own preferences and is not intended as a systematic review of the litterature. Fabio Sánchez, MD, MSc, PhD

[catlist name=-"Research about inflammation"]