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Inflammation Matters Rss

At the heart of psoriasis

Posted on : 06-10-2011 | By : Fabio Sanchez | In : Articles


The insight that psoriasis is more than a skin disorder has been suggested in the international literature since several decades ago. One of the earliest indications that psorias is linked to cardiovascular disease goes back to a report by McDonald CJ and Calabresi P, whom in 1978 published their results on the relationship between psoriasis and occlusive vascular disease (Br J Dermatol 1978; 99: 469–475). Since then, evidence has been accumulating on the relationship between chronic inflammation in psoriasis and increased risk for cardiovascular disease. A huge study from Denmark compared the incidence of atrial fibrillations (heart rhythm disorder) and ischemic stroke (brain damage due to sudden lack of blood supply) between 36 765 patients with mild psoriasis, 2793 with sever psoriasis and 4 478 926 individuals without the disease and found a high risk of such health problems amongst psoriasis patients which seems related to the severity of the disease. This means, the greater the severity the higher the risk. Patients under 50 years of age with severe psoriasis had both higher risk of atrial fibrillation and of ischemich stroke.Details of the investigation can be found here: http://eurheartj.oxfordjournals.org/content/early/2011/08/12/eurheartj.ehr285.abstract


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